Review



rabbit polyclonal anti human irf3 antibody  (Proteintech)


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    Structured Review

    Proteintech rabbit polyclonal anti human irf3 antibody
    (A) Immunohistochemical staining of γH2AX, cGAS, STING, <t>IRF3,</t> and IFN-α was evaluated across multiple TMA slides and categorized as weak (1+), moderate (2+), or strong (3+). (B) Distribution of H-scores for each antibody across 164 cases. H-scores were categorized into two groups: Weak (0–150), Moderate to high (151–300). The Mann–Whitney U test was performed to compare two groups, *p < 0.001. Represents images acquired at 20 × magnification.
    Rabbit Polyclonal Anti Human Irf3 Antibody, supplied by Proteintech, used in various techniques. Bioz Stars score: 96/100, based on 437 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/rabbit+polyclonal+anti+human+irf3+antibody/pmc12915935-281-35-42?v=Proteintech
    Average 96 stars, based on 437 article reviews
    rabbit polyclonal anti human irf3 antibody - by Bioz Stars, 2026-07
    96/100 stars

    Images

    1) Product Images from "Prognostic value of cGAS-STING-IRF3 signaling in cholangiocarcinoma patients"

    Article Title: Prognostic value of cGAS-STING-IRF3 signaling in cholangiocarcinoma patients

    Journal: PLOS One

    doi: 10.1371/journal.pone.0342756

    (A) Immunohistochemical staining of γH2AX, cGAS, STING, IRF3, and IFN-α was evaluated across multiple TMA slides and categorized as weak (1+), moderate (2+), or strong (3+). (B) Distribution of H-scores for each antibody across 164 cases. H-scores were categorized into two groups: Weak (0–150), Moderate to high (151–300). The Mann–Whitney U test was performed to compare two groups, *p < 0.001. Represents images acquired at 20 × magnification.
    Figure Legend Snippet: (A) Immunohistochemical staining of γH2AX, cGAS, STING, IRF3, and IFN-α was evaluated across multiple TMA slides and categorized as weak (1+), moderate (2+), or strong (3+). (B) Distribution of H-scores for each antibody across 164 cases. H-scores were categorized into two groups: Weak (0–150), Moderate to high (151–300). The Mann–Whitney U test was performed to compare two groups, *p < 0.001. Represents images acquired at 20 × magnification.

    Techniques Used: Immunohistochemical staining, Staining, MANN-WHITNEY

    A . (A-C) FFPE from a CCA patients of H&E staining, 20X, scale bar = 100 µm of Well, Moderate and Poorly differentiated papillary subtype. (D-F) Weak (1+), Moderate (2+), or Strong (3+) of IRF3 expression patterns. Represents staining, 20X, scale bar = 100 µm. B . (A-C) FFPE from a CCA patients of H&E staining, 20X, scale bar = 100 µm of Well, Moderate and Poorly differentiated tubular subtype. (D-F) Weak (1+), Moderate (2+), or Strong (3+) of IRF3 expression patterns. Represents staining, 20X, scale bar = 100 µm.
    Figure Legend Snippet: A . (A-C) FFPE from a CCA patients of H&E staining, 20X, scale bar = 100 µm of Well, Moderate and Poorly differentiated papillary subtype. (D-F) Weak (1+), Moderate (2+), or Strong (3+) of IRF3 expression patterns. Represents staining, 20X, scale bar = 100 µm. B . (A-C) FFPE from a CCA patients of H&E staining, 20X, scale bar = 100 µm of Well, Moderate and Poorly differentiated tubular subtype. (D-F) Weak (1+), Moderate (2+), or Strong (3+) of IRF3 expression patterns. Represents staining, 20X, scale bar = 100 µm.

    Techniques Used: Staining, Expressing

    (A–E) Kaplan–Meier survival curves comparing patients with low and moderate-to-high expression of γH2AX, cGAS, STING, IRF3, and IFN-α. P-values were calculated using the log-rank test.
    Figure Legend Snippet: (A–E) Kaplan–Meier survival curves comparing patients with low and moderate-to-high expression of γH2AX, cGAS, STING, IRF3, and IFN-α. P-values were calculated using the log-rank test.

    Techniques Used: Expressing



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    (A) Immunohistochemical staining of γH2AX, cGAS, STING, <t>IRF3,</t> and IFN-α was evaluated across multiple TMA slides and categorized as weak (1+), moderate (2+), or strong (3+). (B) Distribution of H-scores for each antibody across 164 cases. H-scores were categorized into two groups: Weak (0–150), Moderate to high (151–300). The Mann–Whitney U test was performed to compare two groups, *p < 0.001. Represents images acquired at 20 × magnification.
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    Image Search Results


    (A) Immunohistochemical staining of γH2AX, cGAS, STING, IRF3, and IFN-α was evaluated across multiple TMA slides and categorized as weak (1+), moderate (2+), or strong (3+). (B) Distribution of H-scores for each antibody across 164 cases. H-scores were categorized into two groups: Weak (0–150), Moderate to high (151–300). The Mann–Whitney U test was performed to compare two groups, *p < 0.001. Represents images acquired at 20 × magnification.

    Journal: PLOS One

    Article Title: Prognostic value of cGAS-STING-IRF3 signaling in cholangiocarcinoma patients

    doi: 10.1371/journal.pone.0342756

    Figure Lengend Snippet: (A) Immunohistochemical staining of γH2AX, cGAS, STING, IRF3, and IFN-α was evaluated across multiple TMA slides and categorized as weak (1+), moderate (2+), or strong (3+). (B) Distribution of H-scores for each antibody across 164 cases. H-scores were categorized into two groups: Weak (0–150), Moderate to high (151–300). The Mann–Whitney U test was performed to compare two groups, *p < 0.001. Represents images acquired at 20 × magnification.

    Article Snippet: Primary antibodies used included a rabbit polyclonal Gamma H2A.X antibody (phosphor S139) (γH2AFX; dilution 1:400, ab11174; Abcam), rabbit polyclonal anti-human c-GAS antibody (dilution 1:200, Proteintech, US), rabbit polyclonal anti-human STING antibody (dilution 1:3000, Proteintech, US), rabbit polyclonal anti-human IRF3 antibody (dilution 1:800, Proteintech, US), and rabbit polyclonal anti-human IFN alpha antibody (dilution 1:50, Proteintech, US).

    Techniques: Immunohistochemical staining, Staining, MANN-WHITNEY

    A . (A-C) FFPE from a CCA patients of H&E staining, 20X, scale bar = 100 µm of Well, Moderate and Poorly differentiated papillary subtype. (D-F) Weak (1+), Moderate (2+), or Strong (3+) of IRF3 expression patterns. Represents staining, 20X, scale bar = 100 µm. B . (A-C) FFPE from a CCA patients of H&E staining, 20X, scale bar = 100 µm of Well, Moderate and Poorly differentiated tubular subtype. (D-F) Weak (1+), Moderate (2+), or Strong (3+) of IRF3 expression patterns. Represents staining, 20X, scale bar = 100 µm.

    Journal: PLOS One

    Article Title: Prognostic value of cGAS-STING-IRF3 signaling in cholangiocarcinoma patients

    doi: 10.1371/journal.pone.0342756

    Figure Lengend Snippet: A . (A-C) FFPE from a CCA patients of H&E staining, 20X, scale bar = 100 µm of Well, Moderate and Poorly differentiated papillary subtype. (D-F) Weak (1+), Moderate (2+), or Strong (3+) of IRF3 expression patterns. Represents staining, 20X, scale bar = 100 µm. B . (A-C) FFPE from a CCA patients of H&E staining, 20X, scale bar = 100 µm of Well, Moderate and Poorly differentiated tubular subtype. (D-F) Weak (1+), Moderate (2+), or Strong (3+) of IRF3 expression patterns. Represents staining, 20X, scale bar = 100 µm.

    Article Snippet: Primary antibodies used included a rabbit polyclonal Gamma H2A.X antibody (phosphor S139) (γH2AFX; dilution 1:400, ab11174; Abcam), rabbit polyclonal anti-human c-GAS antibody (dilution 1:200, Proteintech, US), rabbit polyclonal anti-human STING antibody (dilution 1:3000, Proteintech, US), rabbit polyclonal anti-human IRF3 antibody (dilution 1:800, Proteintech, US), and rabbit polyclonal anti-human IFN alpha antibody (dilution 1:50, Proteintech, US).

    Techniques: Staining, Expressing

    (A–E) Kaplan–Meier survival curves comparing patients with low and moderate-to-high expression of γH2AX, cGAS, STING, IRF3, and IFN-α. P-values were calculated using the log-rank test.

    Journal: PLOS One

    Article Title: Prognostic value of cGAS-STING-IRF3 signaling in cholangiocarcinoma patients

    doi: 10.1371/journal.pone.0342756

    Figure Lengend Snippet: (A–E) Kaplan–Meier survival curves comparing patients with low and moderate-to-high expression of γH2AX, cGAS, STING, IRF3, and IFN-α. P-values were calculated using the log-rank test.

    Article Snippet: Primary antibodies used included a rabbit polyclonal Gamma H2A.X antibody (phosphor S139) (γH2AFX; dilution 1:400, ab11174; Abcam), rabbit polyclonal anti-human c-GAS antibody (dilution 1:200, Proteintech, US), rabbit polyclonal anti-human STING antibody (dilution 1:3000, Proteintech, US), rabbit polyclonal anti-human IRF3 antibody (dilution 1:800, Proteintech, US), and rabbit polyclonal anti-human IFN alpha antibody (dilution 1:50, Proteintech, US).

    Techniques: Expressing